I am Leo Sin (施延庆), a visiting student at Westlake University, Intelligent Spatial Medicine Lab, supervised by Prof. Haoyang Li. I received my M.S. in Computer Engineering from The University of Hong Kong (supervised by Prof. Grantham Pang) and my B.S. in Electrical Engineering from Soochow University (supervised by Prof. Lu Bo).

My research focuses on 3D perception for surgical and biomedical scenes, spatial omics, and multimodal AI. I am particularly interested in applying generative AI and 3D reconstruction methods such as NeRF and 3DGS to medical imaging and spatial transcriptomics.

Research Interests: Spatial Omics, 3D Reconstruction (NeRF/3DGS), Multimodal Medical AI, Embodied Intelligence, LLM Agent Systems

Tech Writing & Open Source

I consistently publish technical blogs and workflow notes on Zhihu and Xiaohongshu. Across platforms, I currently have around 130 followers and more than 18,000 total reads.

My recent posts focus on practical AI systems, agent engineering, and research workflows. One representative article is AI Workflow Pipeline, where I summarize how to structure multi-stage AI workflows for real-world development.

I also maintain and open-source several research and agent-system projects:

  • LogicVerse: a lightweight and highly decoupled LLM agent framework featuring multi-source configuration, dynamic model factory design, Meta-Agent routing, and a hot-pluggable skill ecosystem.
  • AskThenRearrange: an embodied-agent project on robot questioning strategy planning based on KCQ encoding from real human dialogues, validated through user studies and deployed on a Unitree humanoid robot.

News

  • 2026.02 Joined Westlake University as visiting student.
  • 2026.01 Built Maze Mask at Global Game Jam 2026.
  • 2025.12 Started research internship at Tongji University CDI on robot questioning strategies.
  • 2025.10 Working on autonomous driving digital twin with 3DGS, CARLA, and Autoware.
  • 2025.06 Joined Tab Next (HK) as algorithm engineer intern, developing medical AI chatbot.

Selected Projects

Spatial Omics 3D Atlas

Spatial Omics - 3D Cell Atlas Reconstruction

Westlake University · 2025.02 - present · Visiting Student

Core research on 3D virtual slice interpolation for spatial transcriptomics. The goal is to synthesize virtual intermediate tissue slices between real 2D sections and support 3D cell atlas reconstruction.

Spatial Omics 3D Reconstruction Xenium AnnData
Medical Chatbot Architecture

Medical RAG Chatbot - AI Agent for Imaging Center

Tab Next (HK) · 2025.06 - 2025.09 · Algorithm Engineer Intern

Built a ReAct agent-based medical chatbot for TST Imaging Center, including retrieval, tool calling, LoRA fine-tuning, and multimodal WhatsApp processing.

LLM Agent RAG LoRA vLLM Qwen
AskThenRearrange Project

AskThenRearrange - Robot Questioning Strategy via KCQ Encoding

Tongji University CDI · 2025.12 - 2026.03 · Research Intern

Designed robot questioning strategy planning based on KCQ encoding from real human dialogues, and deployed the resulting policy on a Unitree humanoid robot.

GitHub
Embodied AI LLM HRI Unitree
3DGS Digital Twin

Autonomous Driving Digital Twin - 3DGS + CARLA/Autoware

2025.10 - present

Built an Image to COLMAP to 3D Gaussian Splatting reconstruction pipeline and connected it with CARLA simulation for digital twin experiments.

3DGS COLMAP CARLA Autoware
Maze Mask Game Cover

Maze Mask - GGJ2026 Multiplayer Pixel Game

Global Game Jam 2026 · 2026.01.29 - 2026.01.31

Built a multiplayer online pixel-art game centered on mask power-ups and coin grabbing during Global Game Jam 2026, with contributions in map design, gameplay planning, and mask feature implementation.

Play Online
Game Jam Pixel Art Multiplayer React TypeScript